A flow of vaccine really useful?

<p> immune vaccination in full swing expert three questions about safety issues related to the vaccine <wbr> Beijing News "knowledge Weekly" <wbr> <wbr> <wbr> pharmaceutical companies are stepping up production now a vaccination, .meet the needs of more people vaccinated. .Figure / CFP <wbr> <wbr> <wbr> <wbr> Now, organizations across the country are in the vaccine work. .Beijing also has expanded the scope of the vaccine, as long as people living resident to work in Beijing, with the ID card are entitled to free vaccination. .</ P> <p> <wbr> </ P> <p> At the same time, in the Chinese Internet, on the various rumors that the vaccine more up gradually: the proliferation of the vaccine led to a stream; hit vaccines .more likely to get sick; the doctors themselves are not the vaccine ... ... "A vaccine is playing or not?" Many people are beginning to face such a problem. .We may wish to work together to understand what the real situation of the vaccine. .</ P> <p> <wbr> </ P> <p> 1 vaccine theory </ P> <p> What is the vaccine? .</ P> <p> <wbr> </ P> <p> before the vaccination, this is our first question should know: injected into our bodies, what is it? .</ P> <p> <wbr> </ P> <p> ordinary seasonal flu vaccine has been a lot of years. .To create a vaccine against the virus, a virus must first, with these viruses to produce vaccines. .Although influenza vaccine is made from the virus, but which is not the "toxic", more precisely, with little or no potential to spread toxic power of the virus. .Its main purpose is to produce antibodies in the human body. .</ P> <p> <wbr> </ P> <p> influenza viruses can be divided into "live" and "death" of the two, known as the "live virus (attenuated, live attenuated) vaccine" and " .toxic death (Against Drugs, cracking) vaccine. " ." A serpent's fangs you pull it, the poison sac removed, but the snake is a snake." Huang Union Medical College professor of epidemiology at the beginning of the name for example, "attenuated vaccine, the virus is still complete, but toxicity .reduce it. "</ P> <p> <wbr> </ P> <p>" the menace of the vaccine is equivalent to a section of the snake hacked, and to break the virus, and then made to produce effective antibodies .protein to make the vaccine. "These proteins are antigens, into the vaccine will be based on protein antigens of human antibodies. .</ P> <p> <wbr> </ P> <p> live vaccine and the dead have their own pros and cons of vaccines, live vaccines can often lead to comprehensive immunity, the immune effect of better and longer protection period, .because the live vaccine still has reproductive capability, so no big dose vaccination can reduce the cost, however, must be attenuated live vaccine, technology requirements are relatively high, but, in recent years as the development of molecular immunology, can be achieved in the .gene level, the level of removal of pathogenic virulence factors. .Died vaccine safety is high, but it must increase the dose and frequency of vaccination, so the cost is relatively expensive. .</ P> <p> <wbr> </ P> <p> informed the Ministry of Health, the Chinese all the vaccine is the menace of vaccine. .In the world, the production of the vaccine in different ways the same. .Chinese and European pharmaceutical companies have joined in the vaccine adjuvant in the adjuvant with the assistance of each vaccine can reduce the amount of dead virus, which vaccine viruses with limited vaccine use in more. .The United States has not yet approved the use of adjuvant. .</ P> <p> <wbr> </ P> <p> Influenza H1N1 influenza joint prevention and control mechanism of the Expert Committee Zhao Kai, head of the vaccine after receiving the CCTV interview, academician, said that in July, China's vaccine experts .was facing a "whole virus" or "cracking" vaccine, is "adjuvanted" vaccine doses such as the choice of 8 kinds of problems, and finally they chose a higher degree of security "adjuvanted split vaccine." .</ P> <p> <wbr> </ P> <p> fact, a flu vaccine in China in terms of variety, because it is the menace of the vaccine, the virus is broken, it is "dead", .is not toxic and, therefore, does not exist because the vaccine virus replication reproduction, resulting in expansion of the causal logic of risk of illness linked. .</ P> <p> <wbr> </ P> <p> "vaccine will stimulate the body to increase immunity against the virus, rather than the body is more susceptible to H1N1 influenza." World Health Organization (WHO) China immunohistochemistry .Office immunization project team leader Lisa Carnes (LisaCairns) said. .</ P> <p> <wbr> </ P> <p> 2 production process </ P> <p> Why use eggs? .</ P> <p> <wbr> </ P> <p> notice informed the vaccine, especially those who are allergic to eggs can not be referred to the vaccine. .Eggs, food and a flow of such a relationship between the virus it? .</ P> <p> <wbr> </ P> <p> "influenza viruses grow well in eggs and the eggs easier to get." Kearns said. .Virus and species assigned to the enterprise, they need to be amplified, the egg is to cultivate influenza viruses perfect "mother." .According to the officials after the introduction of qualified researchers will poison the bird seed inoculated into chick embryo sac fluid, over 48-72 hours of harvest, then the killing virus (inactivated) process, after that, and then chemically .the virus break, and then purified, to separate useful components from viral antigens, and finally the sterilization filter, derived vaccine stock solution, diluted, and finally distributed into vaccines. .</ P> <p> <wbr> </ P> <p> is not only a flow of vaccine, in fact, all types of influenza virus vaccines are from WHO. ." Every year, we have to decide what kind of influenza vaccine viruses used in vaccines, we must ensure that the use of the vaccine virus is closest to the current global epidemic of influenza virus type." Kearns said. .</ P> <p> <wbr> </ P> <p> many people worry that usually last for a long time the vaccine development, preclinical testing and clinical trials, several steps are reduced, safety is not guaranteed. ." In fact, as you eat the moon cake, this red bean paste, fruit filling next year is another filling it. Although the virus is new, but the technology is old, new wine into old bottles only." Huang said. .Carnes also said that the virus is a pandemic influenza virus, the vaccine is based on mature production technology of seasonal influenza vaccine production, but because the virus only. .</ P> <p> <wbr> </ P> <p> However, our researchers are so fast on the development, production out of the vaccine, there is a very important reason is that producers in the drug .strains sent to do long before the production preparation, such as the approval process, the authorities also adopted a focus on the country's top vaccine expert and other experts with Chinese characteristics, a unified action to work effectively. .In addition, the vaccine is a very important quantitative aspect of the vaccine in China in the WHO experts have not yet sent the quantitative standard time to explore and look for an alternative to standard materials and methods, early quantitative antigen. ." Just as no weights of, to find items to replace the weights of the same." Previously, Zhao Kai, said in an interview, the group of four age groups, 13,000 volunteers, test, test every pin is 15 micrograms or whether the .30 micrograms, is a shot or two needles. .Subsequently, the group received the standard and then to check, test error of only 3% of all valid and accurate results, which means finding alternative methods adopted standards, and ultimately, the group found that a needle that is 15 micrograms .effective. .The significance of this figure is significant, it means the same limited time to produce more vaccine. .</ P> <p> <wbr> </ P> <p> 3 validity </ P> <p> vaccines really work? .</ P> <p> <wbr> </ P> <p> "If you want to make the vaccine two months ago, I might hesitate, and now the vaccine if available, I will go." Popular science writer .lean camel immunology researchers said, "It now appears that very few adverse reactions, should be safe." </ P> <p> <wbr> </ P> <p> Chinese Center for Disease Control and Prevention, stressed that the effectiveness of the vaccine .3 the overall population over the age of immune protection generated 85% or more. ." You can be interpreted as 85 100 people can protect individuals, but also can be understood as 100 people playing with 15 people did not play as well." Huang said. .</ P> <p> <wbr> </ P> <p> "a lot of people playing the vaccine, but thought he got a flow so that there is a reason." Kearns said, "including pandemic influenza .including vaccines, no vaccine is 100% effective, but they will greatly reduce the risk of disease. "flu vaccine to take effect 14 days after inoculation, the vaccine 1-3 days prior to infection, or injection .Soon after the same soon infected with the virus will get sick. .In addition, some thought he was suffering from a stream of inoculation, theremay in fact just got other influenza or common cold it got. ." All of these cases, people may think that vaccines do not protect them, or the vaccine caused the disease, but these conclusions are wrong." </ P> <p> <wbr> </ P> <p> at press ., China has more than 2,100 people were vaccinated, 1,100 million people prior injection, 15 cases were reported in patients with severe adverse reactions. .Moreover, the causes were noted, there are two cases in the vaccine died after inoculation of the report, the preliminary judging, the first deaths judged as sudden cardiac death, and the vaccine does not matter, yet the second deaths .autopsy report released. .</ P> <p> <wbr> </ P> <p> this, Carnes said, generally speaking, the number of vaccine recipients in China particularly large, so many people vaccinated is difficult to rule out some .inoculated in the hours or days after inoculation death. .This is because some of the inoculation itself with some health problems, such as heart disease and so on. .In other countries, such as Sweden, also had died after inoculation of the vaccine situation. .According to WHO released on November 19 report, so far, a comprehensive inspection of all the deaths have been reported have shown that a flu vaccine did not have a direct link. .</ P> <p> <wbr> </ P> <p> "Overall, we are now known is that the basic safety of the vaccine is no more dangerous than other influenza vaccines, safety is no problem ., no final conclusion validity, theory is useful. "Huang said:" The state is based on voluntary, informed and free to the provision of vaccines, not forced, and every person will make a play based on their own situation .or not to fight the judge. "<wbr> </ P> <p> 【link】 </ P> <p> about influenza viruses </ P> <p> <wbr> </ P> <p> </ P .> <p> micrographs of influenza virus. .Figure / CFP </ P> <p> <wbr> </ P> <p> influenza pandemic virus is a virus. .Three kinds of influenza viruses: A type (influenza A), B-type (B) and C (HCV), three different antigen is distinct from the nuclear material. .A type influenza virus can cause infection in humans and animals, resulting in less severe disease, B-type influenza virus type A disease caused by a moderate than that, and only people are infected, C-type influenza virus is rarely cause disease in humans. .</ P> <p> <wbr> </ P> <p> we know the word of H1N1, H and N represent the surface of influenza virus type A two important antigens: hemagglutinin (H, haemagglutinin .) ceramide antigen and the enzyme (N, neuraminidase), under which, H antigen and N antigen were H1, H2, H3, and N1, N2 several subspecies. .</ P> <p> <wbr> </ P> <p> Dr. Carnes explained, H and N fickle, lead to different types of viruses, these changes become "antigenic drift" (antigenicdrift), usually every 10 .to 40 years, the virus will be presented by the major surface antigens of these changes are likely with different antigens of influenza A virus genes and changes, if major changes occurred antigen, it means that most of the people .no immunity to influenza virus, the epidemic occurred. .A stream is a new virus that people have no immunity. .</ P> <p> edition have written / reporter Kim Yu </ P>.